Topological features in stretching of proteins.

نویسندگان

  • Marek Cieplak
  • Mateusz Sikora
چکیده

In the present article, we highlight the diversity of mechanical clamps, some of them topological in nature, that have been found by making surveys of mechanostability of approximately 18000 proteins within structure-based models. The existence of superstable proteins (with the characteristic unfolding force in the region of 1000 pN) is predicted.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Topological Mixing in Three-Dimensional Porous Media

The topological complexity inherent to all porous media can impart complicated transport dynamics under steady flow conditions. Recently, it has been established [2] that such topological complexity imparts ubiquitous and persistent chaotic advection via a 3D fluid mechanical analogue of the baker’s map. In the presence of molecular diffusion, chaotic Lagrangian dynamics are well-known to impar...

متن کامل

Introducing Potential Key Proteins and Pathways in Human Laryngeal Cancer: A System Biology Approach

The most common malignant neoplasm of the head and neck region is laryngeal cancerwhich presents a significant international health problem. The present study aims to screenpotential proteins related to laryngeal cancer by network analysis to further understandingdisease pathogenesis and biomarker discovery. Differentially expressed proteins were extractedfrom literatures of laryngeal cancer th...

متن کامل

Introducing Potential Key Proteins and Pathways in Human Laryngeal Cancer: A System Biology Approach

The most common malignant neoplasm of the head and neck region is laryngeal cancerwhich presents a significant international health problem. The present study aims to screenpotential proteins related to laryngeal cancer by network analysis to further understandingdisease pathogenesis and biomarker discovery. Differentially expressed proteins were extractedfrom literatures of laryngeal cancer th...

متن کامل

Spectral Quasi-linearization for MHD Nanofluid Stagnation Boundary Layer Flow due to a Stretching/Shrinking Surface

This article concentrates on the effect of MHD heat mass transfer on the stagnation point nanofluid flow over a stretching or shrinking sheet with homogeneous-heterogeneous reactions. The flow analysis is disclosed in the neighborhood of stagnation point. Features of heat transport are characterized with Newtonian heating. The homogeneous-heterogeneous chemical reaction between the fluid and di...

متن کامل

Comparison of massage, static stretching and combination of massage and stretching methods in lower limb muscle on flexibility, anaerobic power and agility tests performance in soccer players

Introduction: The purpose of the study was comparing the three methods including massage, static stretching and combination of massage and stretching in lower limb muscle on flexibility, power and agility tests performance in soccer players. Methods: 45 soccer players contributed in this semi-experimental study. The players were randomly assign in three groups massage (15 cases), stretchi...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Biochemical Society transactions

دوره 41 2  شماره 

صفحات  -

تاریخ انتشار 2013